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Pdf Summary
This document presents a case of a 37-year-old male with ALT-predominant liver enzyme elevation and underlying health issues like obesity, sleep apnea, and diabetes. The patient had liver abnormalities on imaging and biopsy consistent with steatohepatitis. Initial management focused on weight loss through lifestyle modifications, addressing cardiovascular risk factors, abstaining from alcohol, and medication review. If conservative measures fail, options like bariatric procedures and pharmacotherapy are considered. The document poses clinical questions on managing steatohepatitis, introducing pharmacological therapies, and their efficacy. References are provided for further reading on potential treatments like resmetirom and glucagon-like peptide-1 receptor agonists. The comprehensive approach emphasizes lifestyle changes as first-line treatment with medical interventions as alternatives if necessary.
Asset Subtitle
Adam Jacob, DO
Keywords
liver enzyme elevation
steatohepatitis
ALT-predominant
obesity
sleep apnea
diabetes
weight loss
bariatric procedures
pharmacotherapy
pharmacological therapies
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