ASGE Adult and Pediatric Gastroenterology and Endoscopy Board Preparatory and Review Course | 2022-Maratt

Maratt_Polyposis Syndromes and Polyp Management

Pdf Summary

This document provides a review of colorectal cancer (CRC) screening, surveillance, and polyposis/non-polyposis syndromes. The epidemiology of CRC is discussed, highlighting its incidence and mortality rates among different populations. The various pathways of colorectal carcinogenesis are explained, including chromosomal instability, serrated pathway, and microsatellite instability. The risk factors for CRC are identified, including age, sex, race, personal medical history, BMI, and lifestyle factors.<br /><br />The document then reviews the current guidelines for CRC screening and surveillance based on average risk and high-risk individuals. It discusses the recommended age to start screening colonoscopy for average-risk individuals and provides specific guidelines for high-risk individuals based on family history.<br /><br />Different hereditary CRC syndromes are described, including Lynch syndrome, familial adenomatous polyposis (FAP), and hamartomatous syndromes. The genetic basis, clinical features, and screening/surveillance recommendations for each syndrome are discussed.<br /><br />The document concludes with two case scenarios that test the reader's understanding of the material. Additionally, helpful resources for further information are provided, including recent studies and guidelines on CRC screening and management of hereditary syndromes.<br /><br />Overall, this document presents a comprehensive overview of CRC screening, surveillance, and hereditary syndromes in a concise and organized manner. It provides valuable information for healthcare professionals involved in the diagnosis and management of CRC.

Keywords

colorectal cancer screening

surveillance

polyposis syndrome

non-polyposis syndrome

epidemiology of CRC

colorectal carcinogenesis

risk factors for CRC

CRC screening guidelines

high-risk individuals

hereditary CRC syndromes