ASGE Annual GI Advanced Practice Provider Course (On-Demand) - Clinical Case-Based Learning (Day Two) | April 2023-Celiac Disease and Other Diseases of the Small Bowel

Pdf Summary

This document provides information on celiac disease and small bowel disorders. Celiac disease is an autoimmune disorder that affects the small intestine in response to dietary gluten. It is associated with symptoms such as weight loss, diarrhea, malabsorption, and dermatitis herpetiformis. The incidence of celiac disease is increasing, especially in individuals of Northwestern European descent and those with a family history of the disease. The diagnosis of celiac disease involves testing for anti-tissue transglutaminase (TTG) antibodies, and if IgA deficient, IgG-based testing is used. Upper endoscopy with duodenal biopsy is recommended even if serology is negative. Treatment involves adherence to a lifelong gluten-free diet and monitoring for persistent symptoms.<br /><br />The document also discusses small bowel bacterial overgrowth (SIBO), which is characterized by excessive bacteria in the small intestine. Symptoms include bloating, diarrhea, constipation, and abdominal pain. Diagnosis is typically done through breath tests. Treatment for SIBO involves antibiotics such as Rifaximin and dietary measures such as the Low FODMAP diet.<br /><br />The importance of patient education, compliance with gluten-free diet, and long-term follow-up is emphasized. The document also provides guidance on management and monitoring of celiac disease and discusses refractory celiac disease and concurrent disorders associated with celiac disease.<br /><br />References for further reading are provided, including clinical practice guidelines on the diagnosis and management of celiac disease and small intestinal bacterial overgrowth.

Asset Subtitle

Jill Olmstead, DNPc, ANP-BC, CCS-P, FAANP

Keywords

celiac disease

small bowel disorders

autoimmune disorder

gluten

weight loss

diarrhea

malabsorption

dermatitis herpetiformis

family history

gluten-free diet