ASGE Annual GI Advanced Practice Provider Course (Virtual) - Clinical Case-Based Learning (Day Two)

Video Transcription

Video Summary

Dr. Joe Vicari discussed two cases related to liver disease in his presentation. The first case involved a 46-year-old male with abnormal transaminase levels, a history of diabetes, tan skin, and a family history of liver disease. The most likely diagnosis for this patient was hereditary hemochromatosis, caused by a genetic defect leading to iron overload. Dr. Vicari explained the mutations associated with this condition and the importance of genetic testing for diagnosis. Treatment for hemochromatosis involves therapeutic phlebotomy and monitoring to maintain iron levels. The second case discussed a 70-year-old female with abnormal liver enzymes, jaundice, and right upper quadrant pain after starting a medication for a urinary tract infection. This patient was diagnosed with drug-induced liver injury (DILI) and hospitalized for management. Dr. Vicari emphasized the importance of considering DILI in patients with new onset liver disease and the different types of injury patterns seen in DILI. Treatment for DILI includes stopping the offending drug, supportive care, and sometimes medicinal therapy depending on the severity of the condition. Overall, Dr. Vicari highlighted the significance of thorough evaluation, early recognition, and appropriate management in improving outcomes for patients with liver diseases.

Asset Subtitle

Joseph Vicari, MD, MBA, FASGE

Keywords

liver disease

Dr. Joe Vicari

hereditary hemochromatosis

genetic testing

therapeutic phlebotomy

drug-induced liver injury

supportive care