ASGE Annual GI Advanced Practice Provider Course (Virtual) - Clinical Case-based Learning (Day Two) | March 2025-Updates in Inflammatory Bowel Disease

Video Transcription

Video Summary

The video is a detailed lecture on Inflammatory Bowel Disease (IBD), covering key aspects such as its basic pathophysiology, risk stratification, and a treat-to-target approach. The talk emphasizes the complexity of IBD, which involves immune dysregulation, environmental, genetic factors, and the intestinal microbiome. It explains how abnormal immune responses lead to excess pro-inflammatory cytokine production.<br /><br />The session discusses the importance of understanding symptomatology, including bowel movements, stool consistency, and alarm symptoms like nocturnal awakening and tenesmus. The lecturer highlights systemic manifestations, noting that almost half of IBD patients experience symptoms outside the gut, such as joint pain and skin issues, which can precede intestinal symptoms.<br /><br />Moreover, the video explains diagnosis and monitoring strategies, emphasizing tissue biopsies and the use of biomarkers like calprotectin and CRP. It presents a "window of opportunity" in early IBD for tighter monitoring to alter disease progression.<br /><br />The lecture reviews drugs available for IBD, outlines guidelines for their use, discusses steroids' problems, and presents the safety pyramid for medications. Additionally, it underscores the importance of patient-specific treatment strategies and regular health maintenance, including mental health screening and vaccination. The presentation concludes with a reminder about the significance of a comprehensive, patient-centered approach in IBD management.

Asset Subtitle

Amy Stewart, CRNP

Keywords

Inflammatory Bowel Disease

pathophysiology

immune dysregulation

symptomatology

biomarkers

treatment strategies

patient-centered approach

disease monitoring