ASGE Annual GI Advanced Practice Provider Course (Virtual) - Day Two

20_Celiac Disease - Olmstead

Pdf Summary

Celiac disease is a common autoimmune disorder that affects the small intestine in response to dietary gluten. It primarily affects individuals of Northwestern European descent and is associated with certain genetic factors. The typical symptoms of celiac disease include weight loss, diarrhea, malabsorption, and growth failure, among others. However, there can also be atypical symptoms such as iron deficiency anemia, osteoporosis, and psychiatric disorders. <br /><br />To diagnose celiac disease, the recommended tests include anti-tissue transglutaminase (TTG) antibody testing and duodenal biopsy. It is important for patients to be on a gluten-full diet during diagnostic testing. In cases where patients have already started a gluten-free diet, they may need to reintroduce gluten for a period of time before undergoing testing. <br /><br />Management of celiac disease involves lifelong adherence to a gluten-free diet and monitoring for nutritional deficiencies. Patients may benefit from consultation with a dietician and access to advocacy groups. In some cases, patients may experience refractory celiac disease, which requires further evaluation and management. Monitoring includes repeat endoscopy and biopsy, as well as serology testing. <br /><br />It is important to educate patients about the importance of adherence to the gluten-free diet to avoid persistent symptoms, malabsorption, and other complications. Patients should be provided with follow-up programs and routine care to prevent long-term side effects. Overall, celiac disease requires ongoing management and support to ensure optimal outcomes for patients.

Keywords

Celiac disease

autoimmune disorder

small intestine

gluten

genetic factors

diagnosis

gluten-free diet

nutritional deficiencies

refractory celiac disease

management