ASGE Annual GI Advanced Practice Provider Course (Virtual) - Day Two | April 2022-24_Evaluation of Abnormal Liver Tests

24_Evaluation of Abnormal Liver Tests - Martin

Pdf Summary

This document is an evaluation of abnormal liver tests by John A. Martin, MD. The document aims to define liver tests, categorize different types of liver tests, discuss the implications of abnormalities in specific liver tests, and provide guidance on how to work up patients with abnormal liver tests.<br /><br />Liver tests include ALT (alanine aminotransferase), ALP (alkaline phosphatase), bilirubin, γGT (gamma-glutamyl transpeptidase), 5’-nucleotidase, albumin, and PT (prothrombin time). These tests can provide information about liver injury, liver function, and the ability to synthesize proteins and transport bilirubin.<br /><br />The document highlights the importance of understanding the patterns of liver test abnormalities and their clinical implications. For example, elevated AST and ALT levels out of proportion to ALP may indicate hepatocellular injury, while cholestatic pattern abnormalities may suggest biliary obstruction.<br /><br />The management of abnormal liver tests depends on the underlying cause. Viral hepatitis serologies, imaging studies, and liver biopsy may be necessary for further evaluation. The document also provides case studies to illustrate different scenarios and appropriate management strategies.<br /><br />Overall, this document emphasizes the importance of history and physical examination in guiding the workup of abnormal liver tests. It also provides a comprehensive overview of liver test abnormalities and their implications for patient care.

Keywords

abnormal liver tests

evaluation

liver tests

ALT

ALP

bilirubin

γGT

5’-nucleotidase

albumin