ASGE Annual GI Advanced Practice Provider Course (Virtual) - Day Two | April 2022-Evaluation of Abnormal Liver Function Tests

Video Transcription

Video Summary

In the video, the speaker discusses the evaluation of abnormal liver tests. They emphasize the importance of being precise in communication and understanding the physiological meaning of each liver test. They categorize liver tests into liver injury tests, liver synthetic tests, and cholestatic liver enzymes. Liver injury tests such as aspartate amino transferase (AST) and alanine amino transferase (ALT) reflect liver injury, while liver synthetic tests such as albumin and prothrombin time/international normalized ratio (PT/INR) assess liver function. Cholestatic liver enzymes, including alkaline phosphatase (ALP), gamma glutamyl trans peptidase (GGT), and 5'-nucleotidase, indicate problems with bile flow. The speaker discusses patterns of abnormality in liver tests and their implications for different liver diseases. They provide examples and highlight the importance of considering both history and clinical examination in determining the cause of abnormal liver tests. The speaker concludes with practice pearls, emphasizing the need for a systematic approach to evaluating liver test abnormalities and the importance of considering clinical context in directing further investigations.

Asset Subtitle

John Martin, MD, FASGE

Keywords

abnormal liver tests

communication

physiological meaning

liver injury tests

liver synthetic tests

cholestatic liver enzymes

patterns of abnormality

liver diseases