ASGE Annual GI Advanced Practice Provider Course (Virtual) - Onboarding (Day One)

ASGE_GHAPP NordICC Fact Sheet

Pdf Summary

The Nordic-European Initiative on Colorectal Cancer Trial (NordICC Trial) Fact Sheet provides important information about the effectiveness and importance of screening colonoscopy for the detection and prevention of colorectal cancer (CRC). <br /><br />Some key points from the Fact Sheet include:<br /><br />- Screening colonoscopy has overwhelming data demonstrating that it saves lives by detecting and removing adenomas and early cancers.<br />- Compared to other colorectal cancer screening tests, colonoscopy requires less frequent screening.<br />- In the NordICC Trial, only 42% of participants who were invited to undergo colonoscopy actually did so, highlighting the importance of performing the procedure for it to be effective.<br />- The trial estimated that colonoscopy could reduce the incidence of CRC by 31% and the risk of CRC-related death by 50%.<br />- The detection and removal of adenomas during colonoscopy are operator-dependent, and a higher adenoma detection rate (ADR) is associated with a lower risk of future CRC.<br />- Patients with a family history of colon cancer, advanced adenomas, certain hereditary syndromes, or personal history of colon adenomas or cancer should discuss screening and surveillance strategies with their gastroenterologists and not rely on other tests like FIT or stool DNA testing.<br />- It is important to share with referral networks that colonoscopy is the only test that detects and removes adenomas during the same procedure.<br />- In average-risk screening for CRC, colonoscopy every 10 years is recommended if the procedure is negative for adenomas and CRC.<br />- Positive results from stool-based FIT or DNA tests should be followed up with a colonoscopy to confirm or exclude the presence of cancer or high-risk polyps.<br />- Patients with a negative stool DNA test (Cologuard) should repeat the test every 3 years, while a positive test result should lead to a referral for colonoscopy.<br /><br />It is recommended to refer to reliable sources such as the New England Journal of Medicine and the American Society for Gastrointestinal Endoscopy for additional information.

Keywords

NordICC Trial

screening colonoscopy

colorectal cancer

adenomas

early cancers

incidence of CRC

risk of CRC-related death

adenoma detection rate

family history of colon cancer

FIT or stool DNA testing