ASGE Annual GI Advanced Practice Provider Course (Virtual) - Onboarding (Day One) | March 2025-Radiology Studies Case 1: Pancreatic Cyst

Video Transcription

Video Summary

The presentation focuses on diagnosing and managing pancreatic cystic lesions, emphasizing differential diagnosis, evaluation, and risk stratification. Key points include the classification of cysts into benign, pre-malignant, and malignant categories. The presentation introduces a 65-year-old female with an incidental pancreatic cyst detected during a CT scan, with no high-risk symptoms like jaundice or weight loss.<br /><br />In managing such cysts, the presentation emphasizes imaging tools like CT scans, MRIs, and endoscopic ultrasound-guided fine needle aspiration (EUS FNA) for sampling cyst fluid. The analysis of fluid markers such as CEA, amylase, and glucose is crucial in distinguishing between cyst types and potential malignancy.<br /><br />Risk stratification is essential, with surgery indicated for cysts showing high-risk stigmata like obstructive jaundice or enhancing neural nodules. Low-risk cysts can be monitored, while intermediate-risk lesions may require further evaluation. The presentation also covers specific cyst types like IPMNs and mucinous cystic neoplasms, each with distinct management paths influenced by their malignant potential.<br /><br />Ultimately, a systematic approach, informed by updated guidelines and multidisciplinary management, ensures appropriate intervention or surveillance, balancing risk and treatment needs.

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Inessa Khaykis, MD FASGE
Sarah Enslin, PA-C

Keywords

pancreatic cystic lesions

differential diagnosis

risk stratification

imaging tools

fluid markers

surgery indications

multidisciplinary management