ASGE DDW Videos from Around the World | 2025-FROM INDETERMINATE TO SEPTIC THE RAPID TRANSFORMATION OF A PANCREATIC LESION

FROM INDETERMINATE TO SEPTIC THE RAPID TRANSFORMATION OF A PANCREATIC LESION

Video Transcription

Video Summary

The video discusses the transformation of pancreatic cystic lesions (PCLs) and highlights two cases where undifferentiated pancreatic lesions became septic after EUSFNA or FMB procedures. Accurate differentiation between neoplastic and benign cysts, like lymphoepithelial cysts (LECs), is crucial due to the potential transformation risk. Both cases show high infection rates post-sampling, one occurring with and one without prophylactic antibiotics. The report suggests that caution and possible antibiotic use should accompany EUS sampling of LECs, with close monitoring for 4-6 weeks post-intervention. Treatment for infected LEC involves EUS-guided transmural drainage and debridement.

Asset Subtitle

Shailendra Singh

Keywords

pancreatic cystic lesions

EUSFNA

lymphoepithelial cysts

antibiotic prophylaxis

transmural drainage