ASGE DDW Videos from Around the World | 2026-EARLY DETECTION AND SUCCESSFUL ENDOSCOPIC SUBMUCOSAL DISSECTION OF A SUPERFICIAL HYPOPHARYNGEAL CANCER

EARLY DETECTION AND SUCCESSFUL ENDOSCOPIC SUBMUCOSAL DISSECTION OF A SUPERFICIAL HYPOPHARYNGEAL CANCER

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Video Summary

A 71-year-old man with prior esophageal cancer underwent routine upper endoscopy with systematic examination of the oral cavity, oropharynx, and hypopharynx using white light and narrow-band imaging. A subtle 4 cm hypopharyngeal lesion, barely visible on white light, was better detected with NBI and biopsied as high-grade dysplasia. The patient underwent endoscopic submucosal dissection with marking, injection, and clip-line traction, achieving complete en bloc resection. Pathology showed in-situ squamous cell carcinoma with clear margins and no lymphovascular invasion. Recovery was uneventful, and follow-up showed no symptoms, supporting careful screening and ESD as an organ-preserving treatment.

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Submitted by Ylanna Fonseca

Keywords

hypopharyngeal lesion

narrow-band imaging

high-grade dysplasia

endoscopic submucosal dissection

squamous cell carcinoma