ASGE DDW Videos from Around the World | 2026-ENDOSCOPIC CLOSURE OF DUODENO-CUTANEOUS FISTULAE USING A NOVEL TISSUE-ENGINEERED MATRIX SYSTEM

ENDOSCOPIC CLOSURE OF DUODENO-CUTANEOUS FISTULAE USING A NOVEL TISSUE-ENGINEERED MATRIX SYSTEM

Video Transcription

Video Summary

The video presents two cases of chronic duodenocutaneous fistula closed endoscopically using a rolled bovine pericardial tissue matrix plug plus intraluminal endoscopic vacuum therapy. After identifying the fistula tract, the team performed argon plasma coagulation to deepithelialize it, then inserted and anchored the plug to create a mechanical seal and promote healing. In both patients, contrast studies showed no leak within 1–2 weeks, EVT was removed, and oral feeding resumed. The authors conclude this combined technique may be an effective alternative when clips fail in fibrotic, high-output fistulae.

Asset Subtitle

Video Plenary I
Submitted by Amol Bapaye

Keywords

chronic duodenocutaneous fistula

endoscopic closure

bovine pericardial plug

endoscopic vacuum therapy

argon plasma coagulation