ASGE DDW Videos from Around the World | 2026-ENDOSCOPIC NEOPYLORUS FORMATION- A NOVEL INTERVENTION WITH CONCURRENT RESECTION AND PLICATION

ENDOSCOPIC NEOPYLORUS FORMATION- A NOVEL INTERVENTION WITH CONCURRENT RESECTION AND PLICATION

Video Transcription

Video Summary

A 50-year-old woman with complex prior gastric surgeries had refractory GERD, dumping syndrome, and severe postprandial hypoglycemia. During endoscopy, the team performed band-assisted EMR at the gastroesophageal junction, then created a functional neopylorus using endoscopic full-thickness suturing with multiple reinforcing stitches. They also performed plication to narrow the gastroesophageal junction. The procedure aimed to improve gastric emptying and reduce reflux and hypoglycemia. At six-month follow-up, her hypoglycemia nearly resolved and GERD was controlled on once-daily PPI therapy, suggesting endoscopic neopylorus creation with resection and plication can be safe and effective.

Asset Subtitle

Submitted by Badar Hasan

Keywords

endoscopic neopylorus

gastroesophageal junction

refractory GERD

postprandial hypoglycemia

gastric emptying