ASGE DDW Videos from Around the World | 2026-INNOVATING BEYOND ENDOSCOPIC VACUUM THERAPY- ENDOSCOPIC FAT GRAFTING FOR A RADIATION-INDUCED RECTAL PERFORATION

INNOVATING BEYOND ENDOSCOPIC VACUUM THERAPY- ENDOSCOPIC FAT GRAFTING FOR A RADIATION-INDUCED RECTAL PERFORATION

Video Transcription

Video Summary

A 66-year-old man developed a radiation-induced rectal perforation with infected collection after prostate cancer treatment. He declined surgery and was initially managed with endoscopic vacuum therapy, bowel rest, and total parenteral nutrition, with only partial improvement. When healing stalled, the team performed endoscopic autologous abdominal fat grafting: defect margins were cauterized, processed fat was injected around the lesion, and vacuum therapy was restarted. This combined minimally invasive approach led to progressive healing and complete closure of the perforation. The patient resumed oral intake and was discharged.

Asset Subtitle

Submitted by Diogo De Moura

Keywords

radiation-induced rectal perforation

prostate cancer treatment

endoscopic vacuum therapy

autologous abdominal fat grafting

minimally invasive closure