ASGE DDW Videos from Around the World | 2026-STRICTURE PROPHYLAXIS OF POST-ESOPHAGEAL ESD WITH AUTOLOGOUS ADIPOSE-DERIVED STROMAL CELL INJECTION

STRICTURE PROPHYLAXIS OF POST-ESOPHAGEAL ESD WITH AUTOLOGOUS ADIPOSE-DERIVED STROMAL CELL INJECTION

Video Transcription

Video Summary

This report describes a 71-year-old man with a large early esophageal squamous cancer who underwent high-risk endoscopic submucosal dissection involving about 92% of the esophageal circumference. To prevent post-procedure stricture, autologous adipose-derived stromal cells were harvested by liposuction and injected into the resection bed immediately after ESD. The patient also received prednisone. Follow-up endoscopies showed good healing without significant narrowing, and a standard gastroscope passed easily without dilation. His transient dysphagia resolved, and he remained symptom-free. The case suggests this cell-based approach may help prevent severe post-ESD esophageal stenosis.

Asset Subtitle

Video Plenary I
Submitted by Ylanna Fonseca

Meta Tag

Concept Esophageal Stricture

Concept Endoscopic Submucosal Dissection

Concept Autologous Adipose-Derived Stromal Cell

Concept Circumferential resection

Concept Scarring

Keywords

esophageal squamous cancer

endoscopic submucosal dissection

autologous adipose-derived stromal cells

post-ESD stricture prevention

esophageal stenosis

Esophageal Stricture

Endoscopic Submucosal Dissection

Autologous Adipose-Derived Stromal Cell

Circumferential resection

Scarring