ASGE Esophagology: Tailoring Management from Testing to Treatment (On-Demand)

Video Transcription

Video Summary

In this video, Dr. Gary Falk, Professor of Medicine and Director of Physiophagology and Swallowing Center at University of Pennsylvania, discusses the treatment of refractory gastroesophageal reflux disease (GERD). He begins by defining refractory GERD as the persistence of symptoms on stable therapy for eight weeks in individuals who have prior objective evidence of reflux. He emphasizes the importance of accurate diagnosis and discusses the various potential causes of refractory GERD, including mechanical issues at the gastroesophageal junction, noncompliance with PPI medications, and conditions such as reflux hypersensitivity or functional heartburn. The speaker then explores the optimal diagnostic approach, including the use of endoscopy, pH testing, and high-resolution manometry. He also discusses the limitations and benefits of various treatment options, such as weight loss, postural measures, and medication optimization. Additionally, he mentions surgical interventions and alternative therapies like behavioral therapy and neuromodulation. The video concludes with a brief discussion on a new potential medication called von Oppersam. Overall, Dr. Falk provides an overview of the challenges and potential strategies for managing refractory GERD.

Asset Subtitle

Dr. Gary Falk

Keywords

refractory GERD

treatment

diagnosis

causes

treatment options

surgical interventions