ASGE Esophagology: Tailoring Management from Testing to Treatment (On-Demand) | July 2022-Update on Eosinophilic Esophagitis

Video Transcription

Video Summary

In this video, Dr. Iko Hirano, a professor of medicine at Northwestern University School of Medicine, provides an update on eosinophilic esophagitis (EOE). He discusses four misconceptions in the management of EOE in 2022. The first misconception is that symptoms alone are a reliable indicator of disease activity. Dr. Hirano explains that symptoms do not always correlate directly with esophageal inflammation, and that fibrostenotic complications can cause a dissociation between symptoms and the severity of the disease. The second misconception is that maintenance therapy is unnecessary for most patients. Dr. Hirano emphasizes the importance of long-term maintenance therapy for EOE patients to prevent complications such as strictures. The third misconception is that endoscopy can accurately detect strictures. He explains that endoscopy has limited sensitivity for detecting clinically relevant strictures and additional testing may be required. The fourth misconception is that treatment refractory disease is uncommon. Dr. Hirano highlights the need for alternative therapies as a significant proportion of EOE patients do not respond to conventional treatments, such as swallowed topical corticosteroids. He discusses the potential of biologic therapies in addressing this unmet need. The video provides an overview of current challenges and advancements in the management of EOE.

Asset Subtitle

Dr. Ikuo Hirano

Keywords

eosinophilic esophagitis

maintenance therapy

endoscopy

strictures

treatment refractory disease

biologic therapies