ASGE International Sampler (On-Demand) | 2024-Optimal Treatment and Disease Monitoring in EoE

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Dr. Kristle Lee Lynch, Director of the Esophageal and Swallowing Center at the University of Pennsylvania, presented on optimal treatments and disease monitoring for Eosinophilic Esophagitis (EoE) at the ASGE Post Graduate Course during Digestive Diseases Week 2024. The objectives included defining therapy goals, reviewing treatment options, and understanding disease monitoring. EoE is an immune-mediated condition characterized by eosinophilic infiltration causing chronic inflammation, leading to symptoms like dysphagia and heartburn. Therapeutic endpoints include histologic, symptom, and endoscopic improvement. Treatment options include Proton Pump Inhibitors (PPIs), topical steroids like budesonide and fluticasone, and the newly approved drug Dupilumab. Dietary management involves elimination diets or elemental diets with varying success rates. Esophageal dilation may be necessary for strictures. Maintenance therapy is crucial as EoE is a chronic condition prone to relapse if untreated. The future of EoE treatment looks promising with potential novel therapies being studied. Lynch emphasizes shared decision-making, regular follow-ups, and the need for a comprehensive approach to manage EoE effectively.

Asset Subtitle

Kristle Lee Lynch, MD

Keywords

Eosinophilic Esophagitis

EoE

treatment options

disease monitoring

Proton Pump Inhibitors

topical steroids

Dupilumab

dietary management

esophageal dilation

chronic condition