ASGE Recognized Industry Associate (ARIA) Training Program OPEN | October 2025-09 2025 October 9 Open ARIA Presentation 8 Juan Carlos Bucobo Tract in Disease Liver Gallbladder Pancreas

09 2025 October 9 Open ARIA Presentation 8 Juan Carlos Bucobo Tract in Disease Liver Gallbladder Pancreas

Video Transcription

Video Summary

Dr. Bukobu provides a comprehensive review of gastrointestinal diseases, focusing on the liver, gallbladder, and pancreas. Cirrhosis, characterized by liver fibrosis replacing normal tissue, is mainly caused by metabolic-associated fatty liver disease (MAFLD), alcohol-related liver disease, and hepatitis infections. Symptoms include fatigue, jaundice, cognitive impairment (encephalopathy), ascites, and varices, which can cause life-threatening bleeding. Diagnosis relies on biopsy, imaging, and fibrosis scoring. Varices result from portal hypertension and are managed via beta blockers, endoscopic band ligation, and shunting procedures. Ascites involves fluid accumulation treatable by diuretics or shunts. Hepatic encephalopathy, from liver insufficiency, ranges from mild confusion to coma and requires treatment with lactulose or rifaximin.<br /><br />Hepatocellular carcinoma, a common liver cancer linked with cirrhosis and hepatitis B, is screened for regularly; treatment options include surgery, ablation, and transplant. Liver transplantation serves as treatment for cirrhosis, cancer, and acute liver failure.<br /><br />Gallstone disease is common, often asymptomatic but can cause colicky pain or acute cholecystitis when inflamed. Choledocholithiasis involves stones in bile ducts, treated via ERCP with sphincterotomy and stone removal.<br /><br />Pancreatitis, either acute or chronic, caused mainly by gallstones and alcohol, can be life-threatening. Chronic pancreatitis leads to fibrosis and loss of function. Pancreatic cancer risk is increased by smoking and chronic pancreatitis; diagnosis uses imaging and biopsy, with treatment depending on stage.<br /><br />Overall, advances in diagnosis, medical therapies, endoscopic interventions, and surgeries including liver transplant have improved outcomes significantly.

Keywords

gastrointestinal diseases

cirrhosis

hepatocellular carcinoma

gallstone disease

pancreatitis

liver transplantation

portal hypertension