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11 2025 October 9 Open ARIA Presentation 9 Ayokunl ...
11 2025 October 9 Open ARIA Presentation 9 Ayokunle Abegunde Large Intestine IBD and IBS
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Video Transcription
Video Summary
The video discusses inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, their symptoms, pathology, diagnosis, and treatments. Crohn's disease can affect the entire gastrointestinal tract with transmural inflammation and complications like stenosis and fistulae, while ulcerative colitis is limited to the colon with continuous mucosal inflammation. Diagnosis involves clinical assessment, endoscopy, imaging, and histology showing granulomas in Crohn's and pseudopolyps in ulcerative colitis. Treatment aims for remission using medications (aminosalicylates, corticosteroids, immunomodulators, biologics, and small molecules) and sometimes surgery. Microscopic colitis, a related condition, causes chronic diarrhea but with normal colonoscopy findings and requires biopsy for diagnosis. Irritable bowel syndrome (IBS) is a functional disorder with symptoms but no visible disease, diagnosed by Rome IV criteria and treated with lifestyle changes, symptom-specific drugs, and psychological therapies. The video also covers surveillance for IBD-related colorectal cancer and current limits on colon transplantation, noting intestinal transplant as an option for severe cases like short bowel syndrome.
Keywords
Inflammatory Bowel Disease
Crohn's Disease
Ulcerative Colitis
Diagnosis and Treatment
Microscopic Colitis
Irritable Bowel Syndrome
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