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Liver, Gallbladder and Pancreas in Disease
Liver, Gallbladder and Pancreas in Disease
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Video Transcription
Video Summary
The lecture reviews chronic liver disease and common biliary and pancreatic disorders. Liver injury from alcohol, viral hepatitis, metabolic fatty liver disease, autoimmune conditions, or inherited disorders can progress over years from fibrosis to often irreversible cirrhosis. Cirrhosis may cause fatigue, jaundice, muscle wasting, ascites, leg swelling, and encephalopathy. Decompensation can involve life-threatening variceal bleeding, infected ascites, or severe confusion. Evaluation often uses blood tests and noninvasive imaging; patients with cirrhosis need regular liver-cancer surveillance and may require transplant assessment.<br /><br />Metabolic fatty liver disease is increasingly common. Weight loss and healthier lifestyle choices are central to management, alongside emerging therapies. Hepatitis C is usually curable, while hepatitis B can be managed but not cured. Primary sclerosing cholangitis causes bile-duct scarring and is associated with inflammatory bowel disease and increased cancer risk.<br /><br />Gallstones can cause biliary pain, gallbladder inflammation, bile-duct obstruction, and pancreatitis; treatment may include gallbladder surgery or stone removal by ERCP. Acute pancreatitis is commonly caused by gallstones or alcohol and is generally treated with supportive care. Chronic pancreatitis can impair digestion and cause diabetes; enzyme replacement can help with malabsorption. Pancreatic cancer often presents late, sometimes with painless jaundice, and requires multidisciplinary treatment.
Asset Subtitle
Julie Yang
Keywords
cirrhosis
fatty liver disease
hepatitis C
primary sclerosing cholangitis
gallstones
acute pancreatitis
pancreatic cancer
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