ASGE Recognized Industry Associate (ARIA) Training Program for Regeneron and Sanofi

Video Transcription

Video Summary

In this video, Dr. Gonzalez discusses three cases related to dysphagia. The first case involves a 34-year-old male who presented with sudden difficulty swallowing water and chicken, which then resolved. He reports occasional discomfort when swallowing solids and has a history of asthma and seasonal rhinitis. The most likely diagnosis in this case is eosinophilic esophagitis (EOE), but other possibilities such as Schatzki ring and peptic stricture are also considered. The recommended next step is to perform an endoscopy with biopsies to confirm the diagnosis. The endoscopy reveals edema, rings, exudates, and furrows in the esophagus, consistent with EOE. The treatment options discussed include proton pump inhibitors (PPIs), topical corticosteroids, dietary therapy, and the use of Dupilumab. The second case involves a 56-year-old male with worsening dysphagia and a 15-pound weight loss. The most likely diagnosis in this case is esophageal cancer, which is confirmed through endoscopy. The video emphasizes the importance of promptly investigating dysphagia and considering malignancy as a potential cause, especially in older patients. Other risk factors for esophageal cancer, such as reflux, Barrett's esophagus, tobacco use, obesity, and family history, are also discussed. The video concludes with a mention of achalasia and its association with squamous cell cancer, as well as a brief discussion on the transition to the adolescent presentation of EOE.

Asset Subtitle

Nirmala Gonsalves, MD

Keywords

dysphagia

eosinophilic esophagitis

endoscopy

esophageal cancer

weight loss

malignancy