ASGE Recognized Industry Associate (ARIA) Training Program for Regeneron and Sanofi

Pdf Summary

The document discusses several cases of pediatric and adolescent patients with eosinophilic esophagitis (EoE). In Case #1, a 12-year-old male presents with concerns for poor growth. He exhibits symptoms such as being a slow eater, chronic nausea, and burping. Blood testing for celiac disease, UGI, endoscopy, and starting PPI bid are all recommended next steps. Case #2 involves a 16-year-old male who presents to the ED with an acute food impaction. Recommended next steps include a CXR, UGI, endoscopy, or administering Coca Cola in the emergency department. Case #3 discusses a 2-year-old with failure to thrive (FTT) and EoE. The recommended next steps include eliminating all milk and dairy from the diet, starting swallowed steroids, starting an amino acid-based formula, or placing a G-tube for enteral therapy. In Case #4, a 12-year-old with chronic EoE and ulcerative colitis is presented. The patient has been on infliximab treatment and an elemental diet. Case #5 involves a 12-year-old with chronic EoE and ulcerative colitis who has been on tacrolimus and infliximab treatment. The document also discusses the natural history of EoE, its presentation in children and adults, and the different management approaches for pediatric and adolescent patients. The use of dilation in treating EoE is also mentioned, along with the various diet elimination therapies for the condition. The document concludes by discussing the current treatment endpoints and unmet needs in pediatric EoE management.

Asset Subtitle

Jenifer Lightdale, MD, MPH, FASGE

Keywords

pediatric

eosinophilic esophagitis

poor growth

endoscopy

food impaction

failure to thrive

ulcerative colitis

infliximab treatment

diet elimination therapies

treatment endpoints