ASGE Recognized Industry Associate (ARIA) Training Program for Regeneron and Sanofi | June 2023-GI Tract in Disease_Large Intestine_IBD

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This document contains information about gastrointestinal tract diseases, specifically focusing on the large intestine and its associated conditions such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS).<br /><br />Inflammatory bowel disease (IBD) includes Crohn's disease and ulcerative colitis, both of which involve chronic inflammation of the digestive tract. Crohn's disease can affect any part of the digestive tract, while ulcerative colitis primarily affects the colon. Symptoms of Crohn's disease include abdominal pain, diarrhea, and weight loss, while ulcerative colitis is characterized by bloody diarrhea, abdominal pain, and anemia.<br /><br />Diagnosis of IBD involves a combination of clinical, radiographic, endoscopic, and pathologic findings. Treatment goals for IBD include improving quality of life, achieving remission, and maintaining remission. Treatment options range from surgical interventions such as bowel resection to medical treatments like antibiotics, corticosteroids, and biologics.<br /><br />Microscopic colitis is another condition that involves chronic inflammation of the colon, characterized by chronic watery diarrhea and normal colonoscopy results. Treatment options for microscopic colitis include anti-diarrheals, aminosalicylates, corticosteroids, and advanced therapies like biologics.<br /><br />Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder that affects the lower gastrointestinal tract. It is characterized by abdominal pain or discomfort and a change in bowel habits. IBS can be further classified into subtypes based on predominant bowel patterns such as diarrhea, constipation, or mixed.<br /><br />Diagnosis of IBS is based on clinical criteria, and treatment includes lifestyle modifications, symptom-specific drugs, and alternative therapies like hypnotherapy and stress management.<br /><br />Overall, this document provides a brief overview of gastrointestinal tract diseases, their symptoms, diagnostic methods, and treatment options.

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Olufemi Kassim, MD

Keywords

gastrointestinal tract diseases

large intestine

inflammatory bowel disease

Crohn's disease

ulcerative colitis

abdominal pain

diarrhea

weight loss

microscopic colitis

irritable bowel syndrome