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GI Tract in Disease_Large Intestine
GI Tract in Disease_Large Intestine
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Pdf Summary
The document discusses diseases affecting the large intestine, specifically inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). IBD refers to chronic inflammatory conditions of the gastrointestinal (GI) tract, with two types being Crohn's disease and ulcerative colitis. Crohn's disease can affect any part of the GI tract, while ulcerative colitis typically only involves the colon. Diagnosing Crohn's disease can be challenging and often requires multiple tests. Ulcerative colitis is characterized by chronic inflammation restricted to the colon and always involving the rectum. The pathology of these conditions includes architectural distortion, basal plasmacytosis, cryptitis, and crypt abscesses.<br /><br />Microscopic colitis is another condition discussed, with the main types being collagenous and lymphocytic. These types can be diagnosed through microscopic examination of biopsies, as colonoscopy may appear normal. However, it is important to note that the information provided in the document is confidential and for internal use only. It is intended for educational purposes within Sanofi and should not be copied or distributed outside the company or used for promotion.
Asset Subtitle
Tauseef Ali, MD
Keywords
diseases
large intestine
inflammatory bowel disease
IBD
irritable bowel syndrome
Crohn's disease
ulcerative colitis
diagnosis
microscopic colitis
biopsies
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