ASGE Recognized Industry Associate (ARIA) Training Program for Sanofi

Video Transcription

Video Summary

In this video, the speaker discusses eosinophilic esophagitis (EOE). They provide an overview of the epidemiology, clinical presentation, pathophysiology, and natural history of the disease. EOE is described as a chronic immune-mediated food antigen-driven disease that is characterized by symptoms related to esophageal dysfunction and the presence of eosinophil-predominant inflammation in biopsy specimens. The definition of EOE no longer requires inflammation after proton pump inhibitor therapy. The speaker highlights the history and evolution of EOE, as well as the prevalence and incidence rates. They mention that EOE is more common in males and often coexists with other atopic conditions. The clinical presentation of EOE varies by age, with dysphagia and food impactions being the most common symptoms in adults. Diagnostic delay can lead to fibrous stenosis and the need for anti-inflammatory treatment and dilation therapy.

Keywords

eosinophilic esophagitis

EOE

chronic immune-mediated

food antigen-driven disease

esophageal dysfunction

eosinophil-predominant inflammation