Advanced Practice Provider EoE Program (Live/Virtual) | November 2024-The Eosinophilic Attack

Video Transcription

Video Summary

The presentation discusses eosinophilic esophagitis (EOE), a chronic esophageal condition characterized by eosinophilic inflammation. The speaker highlights the key histological features necessary for diagnosing EOE, such as the presence of more than 15 eosinophils per high power field, basal cell hyperplasia, eosinophil abscesses, and lamina propria fibrosis. The challenges in differentiating EOE from reflux esophagitis, due to symptomatic and histological overlaps, are also discussed. The importance of extensive and deep biopsy sampling is emphasized, as EOE can present patchily. Treatment effects on histological features include complete remission, intermediate treatment effects, and disease progression. The speaker underscores the necessity of correlating histological findings with clinical and endoscopic data, urging clinicians to provide comprehensive clinical histories to pathologists for accurate diagnosis. The talk concludes with an encouragement to consider prior pathology reports for context on disease progression or response to treatment. Overall, the session aims to provide a detailed understanding of EOE's histopathology, emphasizing the importance of thorough clinical-pathological correlation for accurate diagnosis and effective management.

Asset Subtitle

Safia Salaria, MD, MMHC

Meta Tag

Concept Eosinophilic Esophagitis

Concept Intraepithelial Eosinophils

Concept Histology

Concept Esophageal Eosinophilia

Concept Basal Cell Hyperplasia

Keywords

eosinophilic esophagitis

histological features

diagnosis

biopsy sampling

clinical-pathological correlation

treatment effects

disease progression

Eosinophilic Esophagitis

Intraepithelial Eosinophils

Histology

Esophageal Eosinophilia

Basal Cell Hyperplasia