Best of GIE | December 2021-Roux-3n-Y Bypass Safety Comparison

Pdf Summary

This study compared the safety and efficacy of endoscopic and surgical revision techniques for weight regain in Roux-en-Y gastric bypass (RYGB) patients with an enlarged gastrojejunal anastomosis (GJA) over a 5-year period. The study involved 62 RYGB patients who underwent either endoscopic or surgical revision. The endoscopic group and surgical group were matched based on several factors, including follow-up, age, sex, body mass index (BMI), initial weight loss, and weight regain.<br /><br />The primary outcome of the study was the comparison of serious adverse event (AE) rates between the two groups. The study found that the AE rate in the endoscopic group was significantly lower (6.5%) compared to the surgical group (29.0%). There were zero serious AEs in the endoscopic group, while six serious AEs occurred in the surgical group. These results suggest that endoscopic revision of the GJA is associated with significantly fewer total and serious AEs compared to surgical revision.<br /><br />Secondary outcomes of the study included weight loss comparisons. The study found no significant difference in weight loss between the endoscopic and surgical groups at 1, 3, and 5 years after revision. This suggests that both techniques provide similar long-term weight loss outcomes for RYGB patients.<br /><br />Overall, this study suggests that endoscopic revision of the GJA is a safer alternative to surgical revision for weight regain in RYGB patients. The study also highlights that both techniques offer similar long-term weight loss outcomes. However, it is important to note that this study has certain limitations, including its retrospective design and the potential for confounding factors. Further research is necessary to validate these findings and determine the optimal approach for GJA revision in RYGB patients.

Asset Subtitle

Complete title: Endoscopic versus surgical gastrojejunal revision for weight regain in Roux-en-Y gastric bypass patients: 5-year safety and efficacy comparison

Meta Tag

Organ & Anatomy Stomach

Procedure Roux-en-Y gastric bypass

Keywords

endoscopic revision

surgical revision

weight regain

Roux-en-Y gastric bypass

gastrojejunal anastomosis

safety

efficacy

adverse events

weight loss outcomes

long-term outcomes