EGD Masterclass: EoE, Strictures, and Pre-malignant Gastric Conditions (On-demand) | January 2023-H. Pylori, Atrophic Gastritis, and Gastric Intestinal Metaplasia

Video Transcription

Video Summary

In this video, Dr. Madhav discusses the topic of Helicobacter pylori (H. pylori) infection and its implications. He explains that H. pylori is a prevalent infection worldwide, with around 70% prevalence in certain regions. In the United States, the prevalence is around 35.6%. Dr. Madhav emphasizes the importance of identifying individuals at risk for H. pylori infection and its potential consequences.<br /><br />He discusses the link between H. pylori infection and the development of gastric cancer, explaining that the infection progresses gradually, starting with chronic inflammation, leading to atrophic gastritis and eventually gastric intestinal metaplasia (GIM) - a condition that predisposes individuals to gastric cancer.<br /><br />Dr. Madhav outlines the significance of detecting H. pylori and the need for eradication therapy to reduce the risk of gastric cancer. He also discusses the role of endoscopy in identifying atrophic gastritis and GIM, as well as the importance of proper sampling and histopathological assessment.<br /><br />The speaker highlights the risk factors for cancer progression, such as the extent of atrophic gastritis and the type of GIM, and discusses the need for individualized surveillance based on these factors. He concludes by emphasizing the importance of a thorough examination during endoscopy and the utilization of specific features and techniques, such as chromoendoscopy and narrowband imaging, to improve the detection of GIM.<br /><br />Overall, this video provides an informative overview of the relationship between H. pylori infection, atrophic gastritis, GIM, and the risk of gastric cancer, as well as the role of endoscopy in management and surveillance.

Keywords

H. pylori infection

prevalence

gastric cancer

atrophic gastritis

GIM