EGD Masterclass: EoE, Strictures, and Pre-malignant Gastric Conditions (Virtual Only) | January 2023-Eosinophilic Esophagitis Medical and Diet Therapy

Video Transcription

Video Summary

The speaker discusses the management of eosinophilic esophagitis (EOE) in this video. They start by mentioning therapeutic options for EOE, including drugs (proton pump inhibitors and swallowed topical corticosteroids), diet therapy (elimination diets, elemental diet, and allergy testing-directed diets), and dilation. They note that proton pump inhibitors are no longer required for diagnosis and are now considered a first-line treatment option. Swallowed topical corticosteroids have shown efficacy in multiple trials, but can cause candidiasis as a side effect. They then discuss the different dietary approaches and mention a recent study comparing a single-food elimination diet to a six-food elimination diet. The results showed similar efficacy for both approaches. Lastly, the speaker mentions the role of biologic therapy, specifically Dupilumab, in the treatment of EOE. Dupilumab has been FDA approved and has shown efficacy in reducing eosinophil counts and improving symptoms. Other advanced therapeutics are also in development. The presentation concludes by emphasizing the importance of shared decision making in treatment selection.

Keywords

eosinophilic esophagitis

therapeutic options

proton pump inhibitors

swallowed topical corticosteroids

biologic therapy