EoE Module 6: Histopathology and Differentiators of EoE-INSTRUCTION MODULE: EoE Module 6

Video Transcription

Video Summary

Dr. Adesola Oje and Dr. Safia Salaria discuss the importance of understanding normal histology to identify pathological changes in gastrointestinal conditions, particularly eosinophilic esophagitis (EOE). They explain that EOE is characterized by eosinophils in the esophageal mucosa and lamina propria fibrosis. Accurate diagnosis requires multiple biopsies from different esophagus sections, given the patchy nature of EOE. They emphasize distinguishing EOE from gastroesophageal reflux disease (GERD), which shares similar histopathologic features. Ensuring detailed clinical information and biopsy location helps pathologists provide better diagnostic support, ultimately improving patient management.

Keywords

eosinophilic esophagitis

gastrointestinal conditions

histology

biopsy

gastroesophageal reflux disease