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EoE ToT Module 4 References
Larsson et al Otolaryngol Head Neck Surg 2011 The ...
Larsson et al Otolaryngol Head Neck Surg 2011 The incidence of esophageal bolus impaction is there a seasonal variation
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The study investigates the seasonal variation in the incidence of esophageal foreign bodies or food impaction, with a particular focus on patients with esophageal bolus impaction at NÄL Medical Centre Hospital, Sweden, from 2004 to 2009. The researchers aimed to determine if there was a seasonal pattern in these incidents and whether this variation differed between patients with and without atopic disorders.<br /><br />A total of 314 consecutive cases were analyzed. After excluding cases involving sharp items, cancer, or atresia, and subdividing these cases based on the presence of atopic disorders, results indicated a higher incidence of esophageal bolus impaction during summer and fall compared to winter and spring. Notably, in patients with atopic disorders, the incidence was significantly greater in fall compared to winter, and overall was higher in summer and fall compared to winter and spring, a pattern not observed in patients without atopic disorders.<br /><br />The study found that the seasonal variation was particularly pronounced in patients with a coexisting atopic condition and suspected eosinophilic esophagitis (EoE), a condition known for its seasonal variability due to aeroallergens. The highest incidences were during the summer and fall. This supports the hypothesis that seasonal allergens might exacerbate eosinophilic esophagitis, leading to increased instances of esophageal bolus impaction.<br /><br />The study also noted a higher occurrence in the lower esophagus, consistent with EoE, which typically presents more prominently in this area.<br /><br />It concludes that the significant seasonal variation in esophageal bolus impaction might be attributed to undiagnosed or diagnosed EoE, especially in patients with atopic disorders. The study suggests that proper biopsies and allergic investigations should be conducted in patients presenting with esophageal bolus impaction, particularly if they have a history of atopic disorders.<br /><br />Author contributions involved initial conception, data acquisition, and statistical analysis, supported by ethics approval and statistical rigor, ensuring the reliability of the findings. The study emphasizes the need for heightened clinical awareness and potential prospective studies to further substantiate these findings.
Keywords
seasonal variation
esophageal foreign bodies
food impaction
atopic disorders
eosinophilic esophagitis
NÄL Medical Centre
summer and fall incidence
aeroallergens
lower esophagus
clinical awareness
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