Masterclass: Colorectal Screening Plus (Virtual) | September 2025-Q and A Session 3

Video Transcription

Video Summary

Dr. Gupta discussed serrated polyposis in IBD patients and emphasized close surveillance using dye chromoendoscopy due to subtle lesion detection. He supports using cap-assisted endoscopy over side-viewing scopes for ampullary exams in FAP patients. Regarding genetics evaluation, patients with over 20 adenomas or under 50 with 10-20 adenomas and family history should be prioritized. For Lynch syndrome, he recommends low-dose aspirin (81 mg), pending upcoming trial results suggesting lower doses are as effective as higher doses in reducing cancer risk with manageable bleeding risk. The mechanism of aspirin’s anti-cancer effect is supported by recent research.

Keywords

serrated polyposis

IBD patients

dye chromoendoscopy

cap-assisted endoscopy

Lynch syndrome aspirin therapy