The Best of ASGE Endoscopy from DDW | June 2021-Precision Medicine for Obesity

Video Transcription

Video Summary

Dr. Costa discusses the problem of obesity and the need for a personalized approach to its treatment. He introduces the concept of obesity phenotypes, which are different subtypes of obesity based on individual variations in pathophysiology and behavior. These phenotypes include hungry brain, hungry gut, emotional hunger, and slow burn. Dr. Costa explains that traditional approaches to obesity treatment have been one-size-fits-all, leading to variable outcomes and limited success. He presents research on identifying and classifying obesity phenotypes, using various measures such as food intake, satiety, emotional eating, and energy expenditure. He discusses the potential benefits of using phenotypes to guide treatment, including improved weight loss outcomes. Dr. Costa also highlights ongoing research in biomarker discovery for obesity phenotyping, which may enable simpler and more accurate diagnosis in the future. Overall, he emphasizes the importance of personalized approaches to obesity treatment and the need to move away from a one-size-fits-all paradigm.

Asset Subtitle

Andres Acosta, MD, PhD

Keywords

obesity

personalized approach

obesity phenotypes

traditional approaches

weight loss outcomes