Updates in Endohepatology | November 2025-Recorded Webinar

Video Transcription

Video Summary

The American Society for Gastrointestinal Endoscopy's Thursday Night Light session on Updates in Endohepatology featured key leaders discussing advances in endoscopic hepatology, including diagnostic and therapeutic techniques for liver disease and portal hypertension. The session highlighted recent progress in endoscopic ultrasound (EUS)-guided liver biopsy and portal pressure gradient (PPG) measurement. Dr. Natalie Cosgrove shared optimized techniques for EUS-guided liver biopsy emphasizing safe needle trajectories and wet suction methods, noting advantages like less pain and ability to sample both lobes. She also described careful hemostasis management and periprocedural antibiotic use for certain patients. Dr. Cosgrove reviewed EUS-guided PPG measurement, contrasting it with traditional transjugular methods, highlighting its direct portal pressure measurement capability, safety, and suitability for combined procedures. Dr. Marvin Yu focused on management of esophageal and gastric varices, reviewing standard therapies like band ligation and sclerotherapy, and rescue options including balloon tamponade and esophageal stenting. He detailed endoscopic ultrasound-guided coil and glue injection for gastric varices, showing improved efficacy and safety over traditional methods. Dr. Jason Samarasinha presented recent research including a multicenter U.S. study validating EUS-guided PPG correlation with liver histology and non-invasive markers, and a randomized trial demonstrating superior biopsy quality and pressure measurement reliability with EUS versus transjugular approaches. He also discussed the ENCOUNTER study comparing EUS and transjugular measurements simultaneously, and emerging applications like endoscopic gastric placation for reducing portal pressure. Panelists emphasized multidisciplinary collaboration, pursuing local hepatology partnerships, and integrating endohepatology techniques into comprehensive care pathways. The session underscored the evolving role of endohepatology, promising more accurate diagnostics, streamlined interventions, and improved patient outcomes in liver disease management.

Keywords

American Society for Gastrointestinal Endoscopy

Endohepatology

Endoscopic hepatology

Liver disease

Portal hypertension

Endoscopic ultrasound-guided liver biopsy

Portal pressure gradient measurement

Esophageal and gastric varices management

EUS-guided coil and glue injection

EUS vs transjugular methods

Multidisciplinary collaboration in hepatology

Endoscopic gastric placation