Which patients with a pancreatic cystic lesions (PCLs) should undergo EUS evaluation? Recent advances in EUS-guided tissue acquisition, imaging, and molecular biomarkers have resulted in improved diagnostic accuracy of pancreatic cystic lesions (PCLs). Currently, clinical assessment, cross-sectional imaging and EUS with fluid analysis (if appropriate) belong to the standard care in patients with PCLs. This session will discuss standard approaches to diagnostic work-up, including cross-sectional imaging assessment, the use of EUS, FNA and needle-based confocal laser endomicroscopy (nCLE) with PCL classification.

• Review indications for performing EUS-FNA in pancreatic cystic lesions (PCL)
• Discuss role and impact of EUS-guided through the needle biopsy forceps in the diagnosis of PCL
• Identify technical pointers to improve safety and success

Christopher J. DiMaio, MD, FASGE
Director of Interventional Endoscopy, Mount Sinai Health System
Professor of Medicine, Icahn School of Medicine at Mount Sinai
New York, NY