The Best of ASGE Endoscopy from DDW (On-Demand) | June 2021-POSE State of the Art

Video Transcription

Video Summary

In this video, Dr. Chris Thompson discusses the state of the art for POSE (Primary Obesity Surgery Endoluminal) in 2021. He starts by acknowledging Dr. Thompson's contributions to the field and celebrating the 10-year anniversary of the bariatric endoscopy SIG, which has now transformed into the ABE (American Bariatric Endoscopy) due to his and Nitin Kumar's work. Dr. Thompson explains various surgical analogs that have inspired endoscopic weight loss procedures, including the vertical banded gastroplasty and the gastric imbrication procedure. He then discusses endoscopic procedures like the Roberto Fogle suturing procedure, the Toga procedure, and the EndoZip procedure. Dr. Thompson goes on to explain the different approaches to performing endoscopic suturing and endoluminal plication. He introduces the POSE procedure, which can be performed by placing plications in the gastric fundus or gastric body. He describes the incisionless operating platform used for the procedure, which includes an operating endoscope with channels for visualization and tissue approximation, a tissue helix device, and tissue anchors. He demonstrates the placement of plications in the gastric fundus using the GPROX device. Dr. Thompson presents early clinical results and mentions a multicenter randomized sham control trial that showed statistically significant but not super superior weight loss results. He then discusses the distal POSE procedure, also known as POSE 2.0, which focuses on reducing the width and length of the stomach. He shares early clinical results from the distal POSE procedure. Finally, he introduces a novel version of the POSE procedure with an antireflux component and describes the placement of plications to address reflux. Dr. Thompson concludes by stating that endoscopic gastric placation is proving to be effective and has an important role in obesity treatment. He emphasizes the durability of the plications and the need for combination therapies and personalized treatment programs.

Asset Subtitle

Christopher Thompson, MD, MHES, MSc, FASGE

Keywords

Primary Obesity Surgery Endoluminal

bariatric endoscopy

endoscopic weight loss procedures

POSE procedure

endoscopic gastric placation